fusion expenditures in the
add up to over $1.4 billion annually. For years, the gold
standard solution in spinal fusion has been autograft.
However, the limitations and problems associated with this
procedure have led more and more surgeons away from autograft
and towards other bone graft augmentation solutions. Bone
Morphagenic Protein (BMP) products have been widely heralded to
be the best solution for bone fusion augmentation. BMP and
other solutions have shown the ability to decrease both the pain
and the morbidity common in hip graft procedures and failed
fusions. However, BMP solutions have also shown an
inability to adequately control bone growth. Medtronic has
spent over $660 million to bring INFUSE to the market.
They are currently generating $680 million in sales annually
alone from INFUSE. A product with the ability to both
enhance fusion (faster/stronger) and control growth is
desperately needed in the marketplace and would be a tremendous
benefit to mankind. NeuroPro Technologies, Inc. is
developing such a solution.
Technologies, Inc. is developing NP3, a solution to the problems
of autograft harvest and failed fusions from alternative graft
materials. Our product utilizes a proven and safe drug,
which has been used for many years by millions of humans
worldwide. By combining this drug with a collagen matrix
carrier, we have enabled the safe and targeted delivery of a
fusion accelerator, while controlling the growth area. NP3
is a superior solution to currently available fusion products,
because NP3 enables directed, targeted, and controlled bone
biggest competitor in the bone fusion augmentation market is
from BMP’s. Other products include: Allograft/Xenograft,
Coral, DBM, and other carrier combo products.
only BMP currently cleared to market by the FDA for spinal
fusion is Medtronic’s INFUSE (BMP-2). Stryker has OP-1
(BMP-7) which has an FDA exemption for compassionate use and is
trying to get FDA clearance to market for spinal fusion.
Several other companies (DePuy,
for example) are working to bring a BMP product to the market.
inquiries regarding NP3, please call us at 209.545.5111.